2r0b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:19, 21 February 2024) (edit) (undo)
 
(17 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2r0b.jpg|left|200px]]
 
-
{{Structure
+
==Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein==
-
|PDB= 2r0b |SIZE=350|CAPTION= <scene name='initialview01'>2r0b</scene>, resolution 1.600&Aring;
+
<StructureSection load='2r0b' size='340' side='right'caption='[[2r0b]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
+
<table><tr><td colspan='2'>[[2r0b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R0B FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
|GENE= STYX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r0b OCA], [https://pdbe.org/2r0b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r0b RCSB], [https://www.ebi.ac.uk/pdbsum/2r0b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r0b ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2r0b TOPSAN]</span></td></tr>
-
 
+
</table>
-
'''Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/STYX_HUMAN STYX_HUMAN] Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). Seems to play a role in spermiogenesis (By similarity).
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2R0B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0B OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r0/2r0b_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r0b ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Almo, S C.]]
+
[[Category: Almo SC]]
-
[[Category: Bain, K T.]]
+
[[Category: Bain KT]]
-
[[Category: Bonanno, J B.]]
+
[[Category: Bonanno JB]]
-
[[Category: Burley, S K.]]
+
[[Category: Burley SK]]
-
[[Category: Freeman, J.]]
+
[[Category: Freeman J]]
-
[[Category: Iizuka, M.]]
+
[[Category: Iizuka M]]
-
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
+
[[Category: Romero R]]
-
[[Category: Romero, R.]]
+
[[Category: Sauder JM]]
-
[[Category: Sauder, J M.]]
+
[[Category: Smith D]]
-
[[Category: Smith, D.]]
+
[[Category: Wasserman S]]
-
[[Category: Wasserman, S.]]
+
-
[[Category: GOL]]
+
-
[[Category: SO4]]
+
-
[[Category: hydrolase]]
+
-
[[Category: new york structural genomix research consortium]]
+
-
[[Category: nysgxrc]]
+
-
[[Category: phosphatase]]
+
-
[[Category: protein phosphatase]]
+
-
[[Category: protein structure initiative]]
+
-
[[Category: psi-2]]
+
-
[[Category: structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:31:23 2008''
+

Current revision

Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein

PDB ID 2r0b

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2r0b"
Personal tools