4rze
From Proteopedia
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==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant== | ==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant== | ||
| - | <StructureSection load='4rze' size='340' side='right' caption='[[4rze]], [[Resolution|resolution]] 2.49Å' scene=''> | + | <StructureSection load='4rze' size='340' side='right'caption='[[4rze]], [[Resolution|resolution]] 2.49Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4rze]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZE OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4rze]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RZE FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rze OCA], [https://pdbe.org/4rze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rze RCSB], [https://www.ebi.ac.uk/pdbsum/4rze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rze ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Anzhong | + | [[Category: Homo sapiens]] |
| - | [[Category: Fengwei | + | [[Category: Large Structures]] |
| - | [[Category: Hangzi | + | [[Category: Anzhong L]] |
| - | [[Category: Li | + | [[Category: Fengwei L]] |
| - | [[Category: Qiao | + | [[Category: Hangzi C]] |
| - | [[Category: Tianwei | + | [[Category: Li L]] |
| - | [[Category: Xuyang | + | [[Category: Qiao W]] |
| - | [[Category: Yuan | + | [[Category: Tianwei L]] |
| - | + | [[Category: Xuyang T]] | |
| + | [[Category: Yuan L]] | ||
Current revision
Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
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Categories: Homo sapiens | Large Structures | Anzhong L | Fengwei L | Hangzi C | Li L | Qiao W | Tianwei L | Xuyang T | Yuan L
