4v1y

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==The structure of the hexameric atrazine chlorohydrolase, AtzA==
==The structure of the hexameric atrazine chlorohydrolase, AtzA==
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<StructureSection load='4v1y' size='340' side='right' caption='[[4v1y]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='4v1y' size='340' side='right'caption='[[4v1y]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4v1y]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V1Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4v1y]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._ADP Pseudomonas sp. ADP]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V1Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4v1x|4v1x]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Atrazine_chlorohydrolase Atrazine chlorohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.8 3.8.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v1y OCA], [https://pdbe.org/4v1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v1y RCSB], [https://www.ebi.ac.uk/pdbsum/4v1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v1y ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v1y RCSB], [http://www.ebi.ac.uk/pdbsum/4v1y PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ATZA_PSESD ATZA_PSESD]] Hydrolytically dechlorinates atrazine to hydroxyatrazine. Dechlorinates also simazine, and desethylatrazine but is not active with melamine, terbutylazine, or desethyldesisopropylatrazine.<ref>PMID:8759853</ref>
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[https://www.uniprot.org/uniprot/ATZA_PSESD ATZA_PSESD] Hydrolytically dechlorinates atrazine to hydroxyatrazine. Dechlorinates also simazine, and desethylatrazine but is not active with melamine, terbutylazine, or desethyldesisopropylatrazine.<ref>PMID:8759853</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4v1y" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atrazine chlorohydrolase]]
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[[Category: Large Structures]]
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[[Category: Balotra, S]]
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[[Category: Pseudomonas sp. ADP]]
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[[Category: Lucent, D]]
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[[Category: Balotra S]]
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[[Category: Newman, J]]
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[[Category: Lucent D]]
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[[Category: Peat, T S]]
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[[Category: Newman J]]
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[[Category: Scott, C]]
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[[Category: Peat TS]]
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[[Category: Warden, A C]]
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[[Category: Scott C]]
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[[Category: Bioremediation]]
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[[Category: Warden AC]]
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[[Category: Dehalogenase]]
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[[Category: Hydrolase]]
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[[Category: Protein evolution]]
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Current revision

The structure of the hexameric atrazine chlorohydrolase, AtzA

PDB ID 4v1y

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