2rcy

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[[Image:2rcy.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound==
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|PDB= 2rcy |SIZE=350|CAPTION= <scene name='initialview01'>2rcy</scene>, resolution 2.300&Aring;
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<StructureSection load='2rcy' size='340' side='right'caption='[[2rcy]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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<table><tr><td colspan='2'>[[2rcy]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RCY FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Pyrroline-5-carboxylate_reductase Pyrroline-5-carboxylate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.2 1.5.1.2]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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|GENE= MAL13P1.284 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 Plasmodium falciparum 3D7])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rcy OCA], [https://pdbe.org/2rcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rcy RCSB], [https://www.ebi.ac.uk/pdbsum/2rcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rcy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8IDC6_PLAF7 Q8IDC6_PLAF7]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rc/2rcy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rcy ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound'''
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==See Also==
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*[[Pyrroline-5-carboxylate reductase|Pyrroline-5-carboxylate reductase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2RCY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RCY OCA].
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[[Category: Large Structures]]
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[[Category: Plasmodium falciparum 3d7]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Pyrroline-5-carboxylate reductase]]
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[[Category: Amani M]]
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[[Category: Single protein]]
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[[Category: Arrowsmith CH]]
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[[Category: Amani, M.]]
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[[Category: Artz JD]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Bochkarev A]]
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[[Category: Artz, J D.]]
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[[Category: Edwards AM]]
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[[Category: Bochkarev, A.]]
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[[Category: Hassanali A]]
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[[Category: Edwards, A M.]]
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[[Category: Hui R]]
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[[Category: Hassanali, A.]]
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[[Category: Khuu C]]
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[[Category: Hui, R.]]
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[[Category: Kozieradzki I]]
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[[Category: Khuu, C.]]
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[[Category: Lew J]]
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[[Category: Kozieradzki, I.]]
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[[Category: Lin YH]]
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[[Category: Lew, J.]]
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[[Category: Ren H]]
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[[Category: Lin, L.]]
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[[Category: Schapira M]]
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[[Category: Ren, H.]]
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[[Category: Sun X]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Sundstrom M]]
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[[Category: Schapira, M.]]
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[[Category: Wasney G]]
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[[Category: Sun, X.]]
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[[Category: Weigelt J]]
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[[Category: Sundstrom, M.]]
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[[Category: Wernimont AK]]
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[[Category: Wasney, G.]]
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[[Category: Zhao Y]]
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[[Category: Weigelt, J.]]
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[[Category: Wernimont, A K.]]
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[[Category: Zhao, Y.]]
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[[Category: GOL]]
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[[Category: MG]]
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[[Category: NAP]]
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[[Category: malaria]]
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[[Category: oxidoreductase]]
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[[Category: pyrroline reductase]]
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[[Category: sgc]]
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[[Category: structural genomic]]
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[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:34:52 2008''
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Current revision

Crystal structure of Plasmodium falciparum pyrroline carboxylate reductase (MAL13P1.284) with NADP bound

PDB ID 2rcy

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OCA

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