4y61

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'''Unreleased structure'''
 
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The entry 4y61 is ON HOLD
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==Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1==
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<StructureSection load='4y61' size='340' side='right'caption='[[4y61]], [[Resolution|resolution]] 3.36&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4y61]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y61 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.358&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y61 OCA], [https://pdbe.org/4y61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y61 RCSB], [https://www.ebi.ac.uk/pdbsum/4y61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y61 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PTPRD_MOUSE PTPRD_MOUSE]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Selective binding between pre- and postsynaptic adhesion molecules can induce synaptic differentiation. Here we report the crystal structure of a synaptogenic trans-synaptic adhesion complex between Slit and Trk-like family member 2 (Slitrk2) and receptor protein tyrosine phosphatase (RPTP) delta. The structure and site-directed mutational analysis revealed the structural basis of splicing-dependent adhesion between Slitrks and type IIa RPTPs for inducing synaptic differentiation.
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Authors: Yamgata, A., Sato, Y., Goto-Ito, S., Uemura, T., Maeda, A., Shiroshima, T., Yoshida, T., Fukai, S.
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Structure of Slitrk2-PTPdelta complex reveals mechanisms for splicing-dependent trans-synaptic adhesion.,Yamagata A, Sato Y, Goto-Ito S, Uemura T, Maeda A, Shiroshima T, Yoshida T, Fukai S Sci Rep. 2015 May 19;5:9686. doi: 10.1038/srep09686. PMID:25989451<ref>PMID:25989451</ref>
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Description:
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Sato, Y]]
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<div class="pdbe-citations 4y61" style="background-color:#fffaf0;"></div>
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[[Category: Fukai, S]]
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[[Category: Yoshida, T]]
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==See Also==
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[[Category: Maeda, A]]
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
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[[Category: Yamgata, A]]
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== References ==
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[[Category: Shiroshima, T]]
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<references/>
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[[Category: Goto-Ito, S]]
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__TOC__
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[[Category: Uemura, T]]
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Fukai S]]
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[[Category: Goto-Ito S]]
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[[Category: Maeda A]]
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[[Category: Sato Y]]
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[[Category: Shiroshima T]]
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[[Category: Uemura T]]
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[[Category: Yamgata A]]
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[[Category: Yoshida T]]

Current revision

Crystal structure of the complex between Slitrk2 LRR1 and PTP delta Ig1-Fn1

PDB ID 4y61

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