2rfq
From Proteopedia
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| - | [[Image:2rfq.gif|left|200px]] | ||
| - | + | ==Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1== | |
| - | + | <StructureSection load='2rfq' size='340' side='right'caption='[[2rfq]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | | | + | <table><tr><td colspan='2'>[[2rfq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhojr Rhojr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RFQ FirstGlance]. <br> |
| - | | | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PS:3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE'>1PS</scene></td></tr> |
| - | | | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hsaA, RHA1_ro04539 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=101510 RHOJR])</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rfq OCA], [https://pdbe.org/2rfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rfq RCSB], [https://www.ebi.ac.uk/pdbsum/2rfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rfq ProSAT], [https://www.topsan.org/Proteins/MCSG/2rfq TOPSAN]</span></td></tr> | |
| - | ''' | + | </table> |
| - | + | == Function == | |
| - | + | [[https://www.uniprot.org/uniprot/HSAA_RHOSR HSAA_RHOSR]] Catalyzes the o-hydroxylation of 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol.<ref>PMID:17264217</ref> | |
| - | == | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rf/2rfq_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rfq ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rhojr]] | ||
| + | [[Category: Chang, C]] | ||
| + | [[Category: Edwards, A M]] | ||
| + | [[Category: Joachimiak, A]] | ||
| + | [[Category: Kagan, O]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Savchenko, A]] | ||
| + | [[Category: Skarina, T]] | ||
| + | [[Category: 3-hsa hydroxylase]] | ||
| + | [[Category: Mcsg]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Rhodococcus sp. rha1]] | [[Category: Rhodococcus sp. rha1]] | ||
| - | [[Category: Single protein]] | ||
| - | [[Category: Chang, C.]] | ||
| - | [[Category: Edwards, A M.]] | ||
| - | [[Category: Joachimiak, A.]] | ||
| - | [[Category: Kagan, O.]] | ||
| - | [[Category: MCSG, Midwest Center for Structural Genomics.]] | ||
| - | [[Category: Savchenko, A.]] | ||
| - | [[Category: Skarina, T.]] | ||
| - | [[Category: 1PS]] | ||
| - | [[Category: 3-hsa hydroxylase]] | ||
| - | [[Category: mcsg]] | ||
| - | [[Category: midwest center for structural genomic]] | ||
| - | [[Category: oxidoreductase]] | ||
| - | [[Category: protein structure initiative]] | ||
| - | [[Category: psi-2]] | ||
| - | [[Category: rhodococcus sp. rha1]] | ||
| - | [[Category: structural genomic]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:40 2008'' | ||
Current revision
Crystal structure of 3-HSA hydroxylase from Rhodococcus sp. RHA1
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