4yw7
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4yw7 is ON HOLD until Mar 20 2017 Authors: Visini, R., Jin, X., Michaud, G., Bergmann, M., Gillon, E., Imberty, A., Stocker, A., Darbre, T., Pieters...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA== | |
| + | <StructureSection load='4yw7' size='340' side='right'caption='[[4yw7]], [[Resolution|resolution]] 1.82Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4yw7]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YW7 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4J0:(2R,3R,4S,5R,6R,2R,3R,4S,5R,6R)-2,2-([(2R,3R,4S,5S,6S)-3,4-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIYL]BIS{1H-1,2,3-TRIAZOLE-1,4-DIYL[(2S,3R,4S,5S,6S)-3,4-DIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIYL]-1H-1,2,3-TRIAZOLE-1,4-DIYLPROPANE-3,1-DIYLOXY})BIS[6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL]'>4J0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yw7 OCA], [https://pdbe.org/4yw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yw7 RCSB], [https://www.ebi.ac.uk/pdbsum/4yw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yw7 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. | ||
| - | + | ==See Also== | |
| - | + | *[[Galactose-binding lectin|Galactose-binding lectin]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Pseudomonas aeruginosa]] |
| - | [[Category: | + | [[Category: Bergmann M]] |
| - | [[Category: | + | [[Category: Darbre T]] |
| - | [[Category: Imberty | + | [[Category: Gillon E]] |
| - | [[Category: | + | [[Category: Imberty A]] |
| - | [[Category: | + | [[Category: Jin X]] |
| - | [[Category: | + | [[Category: Michaud G]] |
| - | [[Category: Stocker | + | [[Category: Pieters R]] |
| - | [[Category: | + | [[Category: Reymond J-L]] |
| + | [[Category: Stocker A]] | ||
| + | [[Category: Visini R]] | ||
Current revision
Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA
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Categories: Large Structures | Pseudomonas aeruginosa | Bergmann M | Darbre T | Gillon E | Imberty A | Jin X | Michaud G | Pieters R | Reymond J-L | Stocker A | Visini R
