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4qx4
From Proteopedia
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==Human Aldose Reductase complexed with a ligand with a new scaffold at 1.26 A== | ==Human Aldose Reductase complexed with a ligand with a new scaffold at 1.26 A== | ||
| - | <StructureSection load='4qx4' size='340' side='right' caption='[[4qx4]], [[Resolution|resolution]] 1.26Å' scene=''> | + | <StructureSection load='4qx4' size='340' side='right'caption='[[4qx4]], [[Resolution|resolution]] 1.26Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qx4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QX4 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4qx4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QX4 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3E2:(3-THIOXO-2,3-DIHYDRO-5H-[1,2,4]TRIAZINO[5,6-B]INDOL-5-YL)ACETIC+ACID'>3E2</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.259Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3E2:(3-THIOXO-2,3-DIHYDRO-5H-[1,2,4]TRIAZINO[5,6-B]INDOL-5-YL)ACETIC+ACID'>3E2</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qx4 OCA], [https://pdbe.org/4qx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qx4 RCSB], [https://www.ebi.ac.uk/pdbsum/4qx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qx4 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4qx4" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Aldose reductase 3D structures|Aldose reductase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Heine A]] |
| - | [[Category: | + | [[Category: Klebe G]] |
| - | [[Category: | + | [[Category: Rechlin C]] |
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| - | + | ||
Current revision
Human Aldose Reductase complexed with a ligand with a new scaffold at 1.26 A
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