4z77
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4z77 is ON HOLD Authors: Rizkallah, P.J., Cole, D.K. Description: Weak TCR binding to an unstable insulin epitope drives type 1 diabetes [[Category...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Weak TCR binding to an unstable insulin epitope drives type 1 diabetes== | |
| + | <StructureSection load='4z77' size='340' side='right'caption='[[4z77]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4z77]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z77 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z77 OCA], [https://pdbe.org/4z77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z77 RCSB], [https://www.ebi.ac.uk/pdbsum/4z77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z77 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HA1D_MOUSE HA1D_MOUSE] Involved in the presentation of foreign antigens to the immune system. | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Cole | + | [[Category: Homo sapiens]] |
| - | [[Category: Rizkallah | + | [[Category: Large Structures]] |
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Cole DK]] | ||
| + | [[Category: Rizkallah PJ]] | ||
Current revision
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
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