2wqk

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==CRYSTAL STRUCTURE OF SURE PROTEIN FROM AQUIFEX AEOLICUS==
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<StructureSection load='2wqk' size='340' side='right' caption='[[2wqk]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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==Crystal Structure of Sure Protein from Aquifex aeolicus==
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<StructureSection load='2wqk' size='340' side='right'caption='[[2wqk]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wqk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2phj 2phj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WQK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wqk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2phj 2phj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WQK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SURE, AQ_832 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqk OCA], [https://pdbe.org/2wqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wqk RCSB], [https://www.ebi.ac.uk/pdbsum/2wqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wqk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wqk RCSB], [http://www.ebi.ac.uk/pdbsum/2wqk PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SURE_AQUAE SURE_AQUAE]] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).
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[https://www.uniprot.org/uniprot/SURE_AQUAE SURE_AQUAE] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wq/2wqk_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wq/2wqk_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wqk ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2wqk" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 5'-nucleotidase]]
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Aquae]]
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[[Category: Large Structures]]
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[[Category: Antonyuk, S V]]
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[[Category: Antonyuk SV]]
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[[Category: Bessho, Y]]
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[[Category: Bessho Y]]
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[[Category: Ellis, M J]]
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[[Category: Ellis MJ]]
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[[Category: Hasnain, S S]]
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[[Category: Hasnain SS]]
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[[Category: Kuramitsu, S]]
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[[Category: Kuramitsu S]]
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[[Category: Structural genomic]]
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[[Category: Strange RW]]
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[[Category: Strange, R W]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: 3-d structure]]
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[[Category: Hydrolase]]
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[[Category: Mixed alpha/beta protein]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Putative acid phosphatase]]
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[[Category: Rsgi]]
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[[Category: Sure protein]]
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Current revision

Crystal Structure of Sure Protein from Aquifex aeolicus

PDB ID 2wqk

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