This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3blj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:10, 30 August 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment==
==Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment==
-
<StructureSection load='3blj' size='340' side='right' caption='[[3blj]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+
<StructureSection load='3blj' size='340' side='right'caption='[[3blj]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3blj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BLJ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3blj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BLJ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PARP15, BAL3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3blj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blj OCA], [https://pdbe.org/3blj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3blj RCSB], [https://www.ebi.ac.uk/pdbsum/3blj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3blj ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3blj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3blj RCSB], [http://www.ebi.ac.uk/pdbsum/3blj PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PAR15_HUMAN PAR15_HUMAN]] Transcriptional repressor. Has ADP-ribosyltransferase activity.
+
[https://www.uniprot.org/uniprot/PAR15_HUMAN PAR15_HUMAN] Transcriptional repressor. Has ADP-ribosyltransferase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blj_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blj_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3blj ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 28: Line 28:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3blj" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]]
+
*[[Poly(ADP-ribose) polymerase 3D structures|Poly(ADP-ribose) polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Large Structures]]
-
[[Category: Berg, S Van Den]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berglund, H]]
+
[[Category: Berglund H]]
-
[[Category: Busam, R D]]
+
[[Category: Busam RD]]
-
[[Category: Collins, R]]
+
[[Category: Collins R]]
-
[[Category: Dahlgren, L G]]
+
[[Category: Dahlgren LG]]
-
[[Category: Edwards, A M]]
+
[[Category: Edwards AM]]
-
[[Category: Flodin, S]]
+
[[Category: Flodin S]]
-
[[Category: Flores, A]]
+
[[Category: Flores A]]
-
[[Category: Graslund, S]]
+
[[Category: Graslund S]]
-
[[Category: Hammarstrom, M]]
+
[[Category: Hammarstrom M]]
-
[[Category: Johansson, I]]
+
[[Category: Johansson I]]
-
[[Category: Kallas, A]]
+
[[Category: Kallas A]]
-
[[Category: Karlberg, T]]
+
[[Category: Karlberg T]]
-
[[Category: Kotenyova, T]]
+
[[Category: Kotenyova T]]
-
[[Category: Lehtio, L]]
+
[[Category: Lehtio L]]
-
[[Category: Moche, M]]
+
[[Category: Moche M]]
-
[[Category: Nilsson, M E]]
+
[[Category: Nilsson ME]]
-
[[Category: Nordlund, P]]
+
[[Category: Nordlund P]]
-
[[Category: Nyman, T]]
+
[[Category: Nyman T]]
-
[[Category: Persson, C]]
+
[[Category: Persson C]]
-
[[Category: Structural genomic]]
+
[[Category: Sagemark J]]
-
[[Category: Sagemark, J]]
+
[[Category: Svensson L]]
-
[[Category: Svensson, L]]
+
[[Category: Thorsell AG]]
-
[[Category: Thorsell, A G]]
+
[[Category: Tresaugues L]]
-
[[Category: Tresaugues, L]]
+
[[Category: Van Den Berg S]]
-
[[Category: Weigelt, J]]
+
[[Category: Weigelt J]]
-
[[Category: Welin, M]]
+
[[Category: Welin M]]
-
[[Category: Bal-3]]
+
-
[[Category: Glycosyltransferase]]
+
-
[[Category: Nad]]
+
-
[[Category: Nucleus]]
+
-
[[Category: Parp]]
+
-
[[Category: Sgc]]
+
-
[[Category: Transcription]]
+
-
[[Category: Transcription regulation]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of human poly(ADP-ribose) polymerase 15, catalytic fragment

PDB ID 3blj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3blj"
Personal tools