4z9m

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==Crystal structure of human sarcomeric mitochondrial creatine kinase==
==Crystal structure of human sarcomeric mitochondrial creatine kinase==
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<StructureSection load='4z9m' size='340' side='right' caption='[[4z9m]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='4z9m' size='340' side='right'caption='[[4z9m]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4z9m]] is a 8 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2gl6 2gl6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z9M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z9M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4z9m]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2gl6 2gl6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Z9M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Creatine_kinase Creatine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.2 2.7.3.2] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z9m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4z9m RCSB], [http://www.ebi.ac.uk/pdbsum/4z9m PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4z9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z9m OCA], [https://pdbe.org/4z9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4z9m RCSB], [https://www.ebi.ac.uk/pdbsum/4z9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4z9m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/KCRS_HUMAN KCRS_HUMAN]] Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
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[https://www.uniprot.org/uniprot/KCRS_HUMAN KCRS_HUMAN] Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
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==See Also==
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*[[Creatine kinase 3D structures|Creatine kinase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Creatine kinase]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bochkarev A]]
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[[Category: Edwards, A M]]
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[[Category: Bountra C]]
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[[Category: Landry, R]]
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[[Category: Edwards AM]]
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[[Category: Nedyalkova, L]]
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[[Category: Landry R]]
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[[Category: Park, H]]
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[[Category: Nedyalkova L]]
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[[Category: Rabeh, W M]]
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[[Category: Park H]]
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[[Category: Structural genomic]]
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[[Category: Rabeh WM]]
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[[Category: Tempel, W]]
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[[Category: Tempel W]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal structure of human sarcomeric mitochondrial creatine kinase

PDB ID 4z9m

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