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5ajw
From Proteopedia
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==Human PFKFB3 in complex with an indole inhibitor 2== | ==Human PFKFB3 in complex with an indole inhibitor 2== | ||
| - | <StructureSection load='5ajw' size='340' side='right' caption='[[5ajw]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='5ajw' size='340' side='right'caption='[[5ajw]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJW FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [https://pdbe.org/5ajw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [https://www.ebi.ac.uk/pdbsum/5ajw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajw ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN] Synthesis and degradation of fructose 2,6-bisphosphate. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 5ajw" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Boyd | + | [[Category: Homo sapiens]] |
| - | [[Category: Brookfield | + | [[Category: Large Structures]] |
| - | [[Category: Critchlow | + | [[Category: Boyd S]] |
| - | [[Category: Cumming | + | [[Category: Brookfield JL]] |
| - | [[Category: Curtis | + | [[Category: Critchlow SE]] |
| - | [[Category: Debreczeni | + | [[Category: Cumming IA]] |
| - | [[Category: Degorce | + | [[Category: Curtis NJ]] |
| - | [[Category: Donald | + | [[Category: Debreczeni JE]] |
| - | [[Category: Evans | + | [[Category: Degorce SL]] |
| - | [[Category: Groombridge | + | [[Category: Donald C]] |
| - | [[Category: Hopcroft | + | [[Category: Evans NJ]] |
| - | [[Category: Jones | + | [[Category: Groombridge S]] |
| - | [[Category: Kettle | + | [[Category: Hopcroft P]] |
| - | [[Category: Lamont | + | [[Category: Jones NP]] |
| - | [[Category: Lewis | + | [[Category: Kettle JG]] |
| - | [[Category: MacFaull | + | [[Category: Lamont S]] |
| - | [[Category: McLoughlin | + | [[Category: Lewis HJ]] |
| - | [[Category: Rigoreau | + | [[Category: MacFaull P]] |
| - | [[Category: Smith | + | [[Category: McLoughlin SB]] |
| - | [[Category: St-Gallay | + | [[Category: Rigoreau LJM]] |
| - | [[Category: Stock | + | [[Category: Smith JM]] |
| - | [[Category: Wheatley | + | [[Category: St-Gallay S]] |
| - | [[Category: Wingfield | + | [[Category: Stock JK]] |
| - | [[Category: Winter | + | [[Category: Wheatley ER]] |
| - | + | [[Category: Wingfield J]] | |
| + | [[Category: Winter J]] | ||
Current revision
Human PFKFB3 in complex with an indole inhibitor 2
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Categories: Homo sapiens | Large Structures | Boyd S | Brookfield JL | Critchlow SE | Cumming IA | Curtis NJ | Debreczeni JE | Degorce SL | Donald C | Evans NJ | Groombridge S | Hopcroft P | Jones NP | Kettle JG | Lamont S | Lewis HJ | MacFaull P | McLoughlin SB | Rigoreau LJM | Smith JM | St-Gallay S | Stock JK | Wheatley ER | Wingfield J | Winter J
