4d4k

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'''Unreleased structure'''
 
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The entry 4d4k is ON HOLD until Paper Publication
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==human PFKFB3 in complex with a pyrrolopyrimidone compound==
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<StructureSection load='4d4k' size='340' side='right'caption='[[4d4k]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
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Authors: Stgallay, S.A., Bennett, N., Critchlow, S., Davies, G., Debreczeni, J.E., Evans, N., Holdgate, G., Jones, N.P., Leach, L., Maman, S., McLoughlin, S., Preston, M., Rigoreau, L., Thomas, A., Walker, G., Walsch, J., Ward, R.A., Wheatley, E., Winter, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4d4k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D4K FirstGlance]. <br>
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Description: human PFKFB3 in complex with a pyrrolopyrimidone compound
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BKE:7-(4-METHOXYPHENYL)-5-PHENYL-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>BKE</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[Category: Wheatley, E]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d4k OCA], [https://pdbe.org/4d4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d4k RCSB], [https://www.ebi.ac.uk/pdbsum/4d4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d4k ProSAT]</span></td></tr>
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[[Category: Rigoreau, L]]
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</table>
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[[Category: Walker, G]]
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== Function ==
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[[Category: Stgallay, S.A]]
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[https://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN] Synthesis and degradation of fructose 2,6-bisphosphate.
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[[Category: Ward, R.A]]
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__TOC__
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[[Category: Preston, M]]
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</StructureSection>
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[[Category: Leach, L]]
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[[Category: Homo sapiens]]
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[[Category: Evans, N]]
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[[Category: Large Structures]]
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[[Category: Debreczeni, J.E]]
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[[Category: Bennett N]]
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[[Category: Critchlow, S]]
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[[Category: Critchlow S]]
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[[Category: Maman, S]]
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[[Category: Davies G]]
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[[Category: Bennett, N]]
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[[Category: Debreczeni JE]]
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[[Category: Mcloughlin, S]]
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[[Category: Evans N]]
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[[Category: Jones, N.P]]
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[[Category: Holdgate G]]
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[[Category: Walsch, J]]
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[[Category: Jones NP]]
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[[Category: Holdgate, G]]
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[[Category: Leach L]]
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[[Category: Davies, G]]
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[[Category: Maman S]]
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[[Category: Winter, J]]
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[[Category: McLoughlin S]]
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[[Category: Thomas, A]]
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[[Category: Preston M]]
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[[Category: Rigoreau L]]
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[[Category: Stgallay SA]]
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[[Category: Thomas A]]
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[[Category: Walker G]]
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[[Category: Walsch J]]
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[[Category: Ward RA]]
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[[Category: Wheatley E]]
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[[Category: Winter J]]

Current revision

human PFKFB3 in complex with a pyrrolopyrimidone compound

PDB ID 4d4k

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