2vph

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(New page: 200px {{Structure |PDB= 2vph |SIZE=350|CAPTION= <scene name='initialview01'>2vph</scene>, resolution 1.90&Aring; |SITE= |LIGAND= |ACTIVITY= [http://en.wikipedia...)
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[[Image:2vph.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain==
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|PDB= 2vph |SIZE=350|CAPTION= <scene name='initialview01'>2vph</scene>, resolution 1.90&Aring;
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<StructureSection load='2vph' size='340' side='right'caption='[[2vph]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2vph]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VPH FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vph OCA], [https://pdbe.org/2vph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vph RCSB], [https://www.ebi.ac.uk/pdbsum/2vph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vph ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PTN4_HUMAN PTN4_HUMAN] May act at junctions between the membrane and the cytoskeleton.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/2vph_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vph ConSurf].
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<div style="clear:both"></div>
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'''CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 4, PDZ DOMAIN'''
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==See Also==
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*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2VPH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Bountra C]]
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[[Category: Bountra, C.]]
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[[Category: Burgess-Brown N]]
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[[Category: Burgess-Brown, N.]]
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[[Category: Edwards A]]
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[[Category: Delft, F Von.]]
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[[Category: Elkins JM]]
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[[Category: Edwards, A.]]
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[[Category: Filippakopoulos P]]
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[[Category: Elkins, J M.]]
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[[Category: Kavanagh K]]
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[[Category: Filippakopoulos, P.]]
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[[Category: Knapp S]]
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[[Category: Kavanagh, K.]]
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[[Category: Pike ACW]]
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[[Category: Knapp, S.]]
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[[Category: Roos AK]]
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[[Category: Pike, A C.W.]]
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[[Category: Wang J]]
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[[Category: Roos, A K.]]
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[[Category: Weigelt J]]
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[[Category: Wang, J.]]
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[[Category: Von Delft F]]
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[[Category: Weigelt, J.]]
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[[Category: cytoplasm]]
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[[Category: cytoskeleton]]
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[[Category: dephosphorylation]]
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[[Category: hydrolase]]
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[[Category: megakaryocyte]]
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[[Category: protein phosphatase]]
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[[Category: ptpmeg]]
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[[Category: ptpn4]]
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[[Category: structural protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:48:05 2008''
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Current revision

Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain

PDB ID 2vph

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