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4ywu

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==Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes==
==Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes==
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<StructureSection load='4ywu' size='340' side='right' caption='[[4ywu]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='4ywu' size='340' side='right'caption='[[4ywu]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ywu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YWU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YWU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ywu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_MGAS1882 Streptococcus pyogenes MGAS1882]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YWU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YWU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SSN:4-OXOBUTANOIC+ACID'>SSN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4oht|4oht]], [[4ogd|4ogd]], [[4ywv|4ywv]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SSN:4-OXOBUTANOIC+ACID'>SSN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Succinate-semialdehyde_dehydrogenase_(NADP(+)) Succinate-semialdehyde dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.79 1.2.1.79] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ywu OCA], [https://pdbe.org/4ywu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ywu RCSB], [https://www.ebi.ac.uk/pdbsum/4ywu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ywu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ywu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ywu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ywu RCSB], [http://www.ebi.ac.uk/pdbsum/4ywu PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0J9X1M8_STRPY A0A0J9X1M8_STRPY]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4ywu" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Succinate-semialdehyde dehydrogenase|Succinate-semialdehyde dehydrogenase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chi, Y M]]
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[[Category: Large Structures]]
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[[Category: Jang, E H]]
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[[Category: Streptococcus pyogenes MGAS1882]]
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[[Category: Lee, K S]]
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[[Category: Chi YM]]
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[[Category: Park, S A]]
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[[Category: Jang EH]]
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[[Category: Es-complex structure]]
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[[Category: Lee KS]]
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[[Category: Oxidoreductase]]
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[[Category: Park SA]]
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[[Category: Streptococcus pyogene]]
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[[Category: Substrate inhibition]]
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[[Category: Succinic semialdehyde dehydrogenase]]
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Current revision

Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes

PDB ID 4ywu

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