4pfm

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==SHEWANELLA BENTHICA DHDPS WITH LYSINE AND PYRUVATE==
==SHEWANELLA BENTHICA DHDPS WITH LYSINE AND PYRUVATE==
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<StructureSection load='4pfm' size='340' side='right' caption='[[4pfm]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
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<StructureSection load='4pfm' size='340' side='right'caption='[[4pfm]], [[Resolution|resolution]] 2.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pfm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PFM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PFM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pfm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_benthica_KT99 Shewanella benthica KT99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PFM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.327&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KPI:(2S)-2-AMINO-6-[(1-HYDROXY-1-OXO-PROPAN-2-YLIDENE)AMINO]HEXANOIC+ACID'>KPI</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KPI:(2S)-2-AMINO-6-[(1-HYDROXY-1-OXO-PROPAN-2-YLIDENE)AMINO]HEXANOIC+ACID'>KPI</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4-hydroxy-tetrahydrodipicolinate_synthase 4-hydroxy-tetrahydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.3.3.7 4.3.3.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pfm OCA], [https://pdbe.org/4pfm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pfm RCSB], [https://www.ebi.ac.uk/pdbsum/4pfm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pfm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pfm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pfm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pfm RCSB], [http://www.ebi.ac.uk/pdbsum/4pfm PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A9DKW4_9GAMM A9DKW4_9GAMM]] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418][SAAS:SAAS00086388]
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[https://www.uniprot.org/uniprot/A9DKW4_9GAMM A9DKW4_9GAMM] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418][SAAS:SAAS00086388]
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==See Also==
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*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 4-hydroxy-tetrahydrodipicolinate synthase]]
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[[Category: Large Structures]]
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[[Category: Dogovski, C]]
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[[Category: Shewanella benthica KT99]]
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[[Category: Panjikar, S]]
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[[Category: Dogovski C]]
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[[Category: Paxman, J J]]
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[[Category: Panjikar S]]
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[[Category: Perugini, M A]]
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[[Category: Paxman JJ]]
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[[Category: Wubben, J M]]
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[[Category: Perugini MA]]
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[[Category: Dihydrodipicolinate synthase]]
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[[Category: Wubben JM]]
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[[Category: Lyase]]
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[[Category: Lysine biosynthesis]]
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[[Category: Tim barrel]]
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SHEWANELLA BENTHICA DHDPS WITH LYSINE AND PYRUVATE

PDB ID 4pfm

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