2zax

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:29, 1 November 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2zax.jpg|left|200px]]
 
-
{{Structure
+
==Crystal Structure of Ferric Cytochrome P450cam==
-
|PDB= 2zax |SIZE=350|CAPTION= <scene name='initialview01'>2zax</scene>, resolution 1.60&Aring;
+
<StructureSection load='2zax' size='340' side='right'caption='[[2zax]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=CAM:CAMPHOR'>CAM</scene> and <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>
+
<table><tr><td colspan='2'>[[2zax]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZAX FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/Camphor_5-monooxygenase Camphor 5-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.1 1.14.15.1]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
|GENE= camC, cyp101 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 Pseudomonas putida])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAM:CAMPHOR'>CAM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zax OCA], [https://pdbe.org/2zax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zax RCSB], [https://www.ebi.ac.uk/pdbsum/2zax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zax ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CPXA_PSEPU CPXA_PSEPU] Involved in a camphor oxidation system.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/za/2zax_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zax ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal Structure of Ferric Cytochrome P450cam'''
+
==See Also==
-
 
+
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2ZAX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZAX OCA].
+
[[Category: Large Structures]]
-
 
+
-
==Reference==
+
-
Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam., Harada K, Sakurai K, Ikemura K, Ogura T, Hirota S, Shimada H, Hayashi T, J Am Chem Soc. 2008 Jan 16;130(2):432-3. Epub 2007 Dec 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18088124 18088124]
+
-
[[Category: Camphor 5-monooxygenase]]
+
[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
-
[[Category: Single protein]]
+
[[Category: Harada K]]
-
[[Category: Harada, K.]]
+
[[Category: Hayashi T]]
-
[[Category: Hayashi, T.]]
+
[[Category: Sakurai K]]
-
[[Category: Sakurai, K.]]
+
[[Category: Shimada H]]
-
[[Category: Shimada, H.]]
+
[[Category: Tsukihara T]]
-
[[Category: Tsukihara, T.]]
+
-
[[Category: CAM]]
+
-
[[Category: HEM]]
+
-
[[Category: K]]
+
-
[[Category: TRS]]
+
-
[[Category: camphor-hydroxylase]]
+
-
[[Category: heme]]
+
-
[[Category: iron]]
+
-
[[Category: membrane]]
+
-
[[Category: metal-binding]]
+
-
[[Category: monooxygenase]]
+
-
[[Category: oxidoreductase]]
+
-
[[Category: p450cam]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:53:25 2008''
+

Current revision

Crystal Structure of Ferric Cytochrome P450cam

PDB ID 2zax

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zax"
Personal tools