4zra
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4zra is ON HOLD Authors: Martinot, A.J., Farrow, M., Bai, L., Layre, E., Cheng, T.Y., Tsai, J.H.C., Iqbal, J., Annand, J., Sullivan, Z., Hussain, M....) |
|||
(8 intermediate revisions not shown.) | |||
Line 1: | Line 1: | ||
- | '''Unreleased structure''' | ||
- | + | ==CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE== | |
- | + | <StructureSection load='4zra' size='340' side='right'caption='[[4zra]], [[Resolution|resolution]] 1.83Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[4zra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZRA FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83Å</td></tr> | |
- | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4RF:TRIPALMITOYLGLYCEROL'>4RF</scene></td></tr> |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zra OCA], [https://pdbe.org/4zra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zra RCSB], [https://www.ebi.ac.uk/pdbsum/4zra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zra ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
- | [[Category: | + | == Function == |
- | [[Category: | + | [https://www.uniprot.org/uniprot/LPRG_MYCTU LPRG_MYCTU] TLR2 agonist that can inhibit primary human macrophage MHC-II Ag processing. Required for Rv1410c (P55) activity.<ref>PMID:15294983</ref> <ref>PMID:18156250</ref> |
- | [[Category: Hussain | + | == References == |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Rubin | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
- | [[Category: | + | [[Category: Annand J]] |
- | [[Category: | + | [[Category: Bai L]] |
- | [[Category: Sullivan | + | [[Category: Cheng TY]] |
- | [[Category: | + | [[Category: Farrow M]] |
+ | [[Category: Hussain M]] | ||
+ | [[Category: Iqbal J]] | ||
+ | [[Category: Layre E]] | ||
+ | [[Category: Martinot AJ]] | ||
+ | [[Category: Moody DB]] | ||
+ | [[Category: Rubin EJ]] | ||
+ | [[Category: Sacchettini J]] | ||
+ | [[Category: Seeliger J]] | ||
+ | [[Category: Sullivan Z]] | ||
+ | [[Category: Tsai JHC]] |
Current revision
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS LPRG BINDING TO TRIACYLGLYCERIDE
|
Categories: Large Structures | Mycobacterium tuberculosis H37Rv | Annand J | Bai L | Cheng TY | Farrow M | Hussain M | Iqbal J | Layre E | Martinot AJ | Moody DB | Rubin EJ | Sacchettini J | Seeliger J | Sullivan Z | Tsai JHC