2zbt
From Proteopedia
(Difference between revisions)
| (11 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2zbt.jpg|left|200px]] | ||
| - | + | ==Crystal structure of pyridoxine biosynthesis protein from Thermus thermophilus HB8== | |
| - | + | <StructureSection load='2zbt' size='340' side='right'caption='[[2zbt]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | | | + | <table><tr><td colspan='2'>[[2zbt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZBT FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zbt OCA], [https://pdbe.org/2zbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zbt RCSB], [https://www.ebi.ac.uk/pdbsum/2zbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zbt ProSAT], [https://www.topsan.org/Proteins/RSGI/2zbt TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | '' | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/PDXS_THET8 PDXS_THET8] Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.[HAMAP-Rule:MF_01824] | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zb/2zbt_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zbt ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [[ | + | __TOC__ |
| - | [ | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Thermus thermophilus HB8]] |
| - | [[Category: | + | [[Category: Ebihara A]] |
| - | [[Category: | + | [[Category: Fujimoto Y]] |
| - | [[Category: | + | [[Category: Kuramitsu S]] |
| - | [[Category: | + | [[Category: Manzoku M]] |
| - | [[Category: | + | [[Category: Yokoyama S]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of pyridoxine biosynthesis protein from Thermus thermophilus HB8
| |||||||||||
