4x5s

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==The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.==
==The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.==
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<StructureSection load='4x5s' size='340' side='right' caption='[[4x5s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4x5s' size='340' side='right'caption='[[4x5s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4x5s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X5S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4x5s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurihydrogenibium_azorense Sulfurihydrogenibium azorense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X5S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AZM:5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>AZM</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZM:5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>AZM</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x5s RCSB], [http://www.ebi.ac.uk/pdbsum/4x5s PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x5s OCA], [https://pdbe.org/4x5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x5s RCSB], [https://www.ebi.ac.uk/pdbsum/4x5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x5s ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/C1DTU5_SULAA C1DTU5_SULAA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4x5s" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carbonate dehydratase]]
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[[Category: Large Structures]]
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[[Category: Alterio, V]]
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[[Category: Sulfurihydrogenibium azorense]]
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[[Category: Fiore, A Di]]
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[[Category: Alterio V]]
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[[Category: Simone, G De]]
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[[Category: De Simone G]]
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[[Category: Alpha bacterial carbonic anhydrase]]
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[[Category: Di Fiore A]]
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[[Category: Enzyme-inhibitor complex]]
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[[Category: Lyase]]
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The crystal structure of an alpha carbonic anhydrase from the extremophilic bacterium Sulfurihydrogenibium azorense.

PDB ID 4x5s

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