4yl1
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structures of mPGES-1 Inhibitor Complexes== | |
| + | <StructureSection load='4yl1' size='340' side='right'caption='[[4yl1]], [[Resolution|resolution]] 1.41Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4yl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YL1 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4U8:5-(4-TERT-BUTYLPHENYL)-1-[4-(PROPAN-2-YLOXY)PHENYL]-1H-INDOLE-2-CARBOXYLIC+ACID'>4U8</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yl1 OCA], [https://pdbe.org/4yl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yl1 RCSB], [https://www.ebi.ac.uk/pdbsum/4yl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yl1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PTGES_HUMAN PTGES_HUMAN] Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).<ref>PMID:18682561</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Prostaglandin E synthase|Prostaglandin E synthase]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Fisher | + | </StructureSection> |
| - | [[Category: Kuklish | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Antonysamy S]] | ||
| + | [[Category: Fisher MJ]] | ||
| + | [[Category: Kuklish SL]] | ||
| + | [[Category: Luz JG]] | ||
Current revision
Crystal Structures of mPGES-1 Inhibitor Complexes
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