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366d

From Proteopedia

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[[Image:366d.gif|left|200px]]
 
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{{Structure
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==1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX==
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|PDB= 366d |SIZE=350|CAPTION= <scene name='initialview01'>366d</scene>, resolution 1.30&Aring;
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<StructureSection load='366d' size='340' side='right'caption='[[366d]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=DA6:6-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE'>DA6</scene>
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<table><tr><td colspan='2'>[[366d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=366D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=366D FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=DA6:6-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE'>DA6</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=366d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=366d OCA], [https://pdbe.org/366d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=366d RCSB], [https://www.ebi.ac.uk/pdbsum/366d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=366d ProSAT]</span></td></tr>
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</table>
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'''1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX'''
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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==About this Structure==
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[[Category: Adams A]]
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366D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=366D OCA].
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[[Category: Cardin CJ]]
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[[Category: Denny WA]]
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==Reference==
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[[Category: Thorpe JH]]
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Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10052960 10052960]
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[[Category: Todd AK]]
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[[Category: Protein complex]]
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[[Category: Adams, A.]]
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[[Category: Cardin, C J.]]
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[[Category: Denny, W A.]]
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[[Category: Thorpe, J H.]]
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[[Category: Todd, A K.]]
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[[Category: DA6]]
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[[Category: dna]]
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[[Category: drug intercalation]]
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[[Category: major groove binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:55:09 2008''
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Current revision

1.3 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/6-BROMO-9-AMINO-DACA COMPLEX

PDB ID 366d

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