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3b53

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[[Image:3b53.jpg|left|200px]]
 
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{{Structure
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==Ni,Fe-CODH-320 mV state==
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|PDB= 3b53 |SIZE=350|CAPTION= <scene name='initialview01'>3b53</scene>, resolution 1.500&Aring;
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<StructureSection load='3b53' size='340' side='right'caption='[[3b53]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene> and <scene name='pdbligand=B51:NICKEL/IRON/SULFUR CLUSTER'>B51</scene>
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<table><tr><td colspan='2'>[[3b53]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Carboxydothermus_hydrogenoformans_Z-2901 Carboxydothermus hydrogenoformans Z-2901]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B53 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Carbon-monoxide_dehydrogenase_(acceptor) Carbon-monoxide dehydrogenase (acceptor)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.99.2 1.2.99.2]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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|GENE= cooS2, cooSII ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=129958 Carboxydothermus hydrogenoformans])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=WCC:FE(3)-NI(1)-S(4)+CLUSTER'>WCC</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b53 OCA], [https://pdbe.org/3b53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b53 RCSB], [https://www.ebi.ac.uk/pdbsum/3b53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b53 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COOS2_CARHZ COOS2_CARHZ] CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH) (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/3b53_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3b53 ConSurf].
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<div style="clear:both"></div>
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'''Ni,Fe-CODH-320 mV state'''
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==See Also==
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*[[Carbon monoxide dehydrogenase 3D structures|Carbon monoxide dehydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3B53 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Carboxydothermus_hydrogenoformans Carboxydothermus hydrogenoformans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B53 OCA].
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[[Category: Carboxydothermus hydrogenoformans Z-2901]]
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[[Category: Carbon-monoxide dehydrogenase (acceptor)]]
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[[Category: Large Structures]]
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[[Category: Carboxydothermus hydrogenoformans]]
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[[Category: Dobbek H]]
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[[Category: Single protein]]
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[[Category: Jeoung JH]]
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[[Category: Dobbek, H.]]
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[[Category: Jeoung, J H.]]
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[[Category: B51]]
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[[Category: FE2]]
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[[Category: FES]]
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[[Category: SF4]]
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[[Category: 4fe-4]]
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[[Category: cluster c]]
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[[Category: cytoplasm]]
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[[Category: iron]]
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[[Category: iron-sulfur]]
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[[Category: membrane]]
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[[Category: metal-binding]]
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[[Category: nickel]]
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[[Category: oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:56:10 2008''
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Current revision

Ni,Fe-CODH-320 mV state

PDB ID 3b53

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