Sandbox WI08
From Proteopedia
(Difference between revisions)
(New page: ==Sandbox WI08== <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''> This is a default text for your page '''Sandbox WI08'''. Click above o...) |
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==Sandbox WI08== | ==Sandbox WI08== | ||
| - | <StructureSection load=' | + | <StructureSection load='1hqk.pdb' size='340' side='right' caption='I am a homo-60-mer' scene=''> |
This is a default text for your page '''Sandbox WI08'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Sandbox WI08'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
| - | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10. | + | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1038/nature06387</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. |
== Function == | == Function == | ||
| - | + | Some things have function | |
== Disease == | == Disease == | ||
| - | + | Disease is bad | |
== Relevance == | == Relevance == | ||
| - | + | Most things aren't relevant | |
== Structural highlights == | == Structural highlights == | ||
| - | + | ||
| + | 1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. | ||
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| + | Tacrine is a reversible inhibitor of cholinesterase. It was the first FDA approved drug for the treatment of Alzheimer's disease. | ||
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| + | Tacrine’s ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (W84 and F330). | ||
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| + | Pubmed 8415649 | ||
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| + | This example is at http://proteopedia.org/w/Proteopedia:DIY:Scenes | ||
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</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Current revision
Sandbox WI08
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References
- ↑ Hessa T, Meindl-Beinker NM, Bernsel A, Kim H, Sato Y, Lerch-Bader M, Nilsson I, White SH, von Heijne G. Molecular code for transmembrane-helix recognition by the Sec61 translocon. Nature. 2007 Dec 13;450(7172):1026-30. PMID:18075582 doi:http://dx.doi.org/10.1038/nature06387
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
