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2n3d
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2n3d is ON HOLD Authors: Shi, C., Fricke, P., Lin, L., Chevelkov, V., Wegstroth, M., Becker, S., Thanbichler, M., Lange, A. Description: Atomic str...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Atomic structure of the cytoskeletal bactofilin BacA revealed by solid-state NMR== | |
| + | <StructureSection load='2n3d' size='340' side='right'caption='[[2n3d]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2n3d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caulobacter_vibrioides_CB15 Caulobacter vibrioides CB15]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N3D FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solid-state NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n3d OCA], [https://pdbe.org/2n3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n3d RCSB], [https://www.ebi.ac.uk/pdbsum/2n3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n3d ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9A753_CAUVC Q9A753_CAUVC] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Bactofilins are a recently discovered class of cytoskeletal proteins of which no atomic-resolution structure has been reported thus far. The bacterial cytoskeleton plays an essential role in a wide range of processes, including morphogenesis, cell division, and motility. Among the cytoskeletal proteins, the bactofilins are bacteria-specific and do not have a eukaryotic counterpart. The bactofilin BacA of the species Caulobacter crescentus is not amenable to study by x-ray crystallography or solution nuclear magnetic resonance (NMR) because of its inherent noncrystallinity and insolubility. We present the atomic structure of BacA calculated from solid-state NMR-derived distance restraints. We show that the core domain of BacA forms a right-handed beta helix with six windings and a triangular hydrophobic core. The BacA structure was determined to 1.0 A precision (heavy-atom root mean square deviation) on the basis of unambiguous restraints derived from four-dimensional (4D) HN-HN and 2D C-C NMR spectra. | ||
| - | + | Atomic-resolution structure of cytoskeletal bactofilin by solid-state NMR.,Shi C, Fricke P, Lin L, Chevelkov V, Wegstroth M, Giller K, Becker S, Thanbichler M, Lange A Sci Adv. 2015 Dec 4;1(11):e1501087. doi: 10.1126/sciadv.1501087. eCollection 2015, Dec. PMID:26665178<ref>PMID:26665178</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Becker | + | <div class="pdbe-citations 2n3d" style="background-color:#fffaf0;"></div> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Caulobacter vibrioides CB15]] |
| - | [[Category: Shi | + | [[Category: Large Structures]] |
| - | [[Category: Wegstroth | + | [[Category: Becker S]] |
| + | [[Category: Chevelkov V]] | ||
| + | [[Category: Fricke P]] | ||
| + | [[Category: Giller K]] | ||
| + | [[Category: Lange A]] | ||
| + | [[Category: Lin L]] | ||
| + | [[Category: Shi C]] | ||
| + | [[Category: Thanbichler M]] | ||
| + | [[Category: Wegstroth M]] | ||
Current revision
Atomic structure of the cytoskeletal bactofilin BacA revealed by solid-state NMR
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