4xco

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==Signal-sequence induced conformational changes in the signal recognition particle==
==Signal-sequence induced conformational changes in the signal recognition particle==
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<StructureSection load='4xco' size='340' side='right' caption='[[4xco]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='4xco' size='340' side='right'caption='[[4xco]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xco]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XCO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XCO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xco]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XCO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ndb|3ndb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xco OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xco RCSB], [http://www.ebi.ac.uk/pdbsum/4xco PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xco OCA], [https://pdbe.org/4xco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xco RCSB], [https://www.ebi.ac.uk/pdbsum/4xco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xco ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SRP54_METJA SRP54_METJA]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.[HAMAP-Rule:MF_00306] [[http://www.uniprot.org/uniprot/SRP19_METJA SRP19_METJA]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP (By similarity).
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[https://www.uniprot.org/uniprot/SRP19_METJA SRP19_METJA] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4xco" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Signal recognition particle protein|Signal recognition particle protein]]
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*[[Signal recognition particle 3D structures|Signal recognition particle 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hainzl, T]]
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[[Category: Large Structures]]
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[[Category: Sauer-Eriksson, A E]]
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[[Category: Methanocaldococcus jannaschii]]
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[[Category: Recombinant fusion protein]]
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[[Category: Hainzl T]]
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[[Category: Rna binding protein]]
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[[Category: Sauer-Eriksson AE]]
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[[Category: Rna structure]]
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[[Category: Signal recognition particle]]
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[[Category: Signal sequence]]
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Signal-sequence induced conformational changes in the signal recognition particle

PDB ID 4xco

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