This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5bzn
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5bzn is ON HOLD Authors: Liu, L.K., Finzel, B.C. Description: Crystal structure of the murine cd44 hyaluronan binding domain complex with a small m...) |
|||
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule== | |
| + | <StructureSection load='5bzn' size='340' side='right'caption='[[5bzn]], [[Resolution|resolution]] 1.23Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5bzn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZN FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4XD:2-(2-METHOXYETHYL)-1,2,3,4-TETRAHYDROISOQUINOLIN-8-AMINE'>4XD</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzn OCA], [https://pdbe.org/5bzn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzn RCSB], [https://www.ebi.ac.uk/pdbsum/5bzn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. | ||
| - | + | ==See Also== | |
| - | + | *[[CD44|CD44]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Finzel | + | [[Category: Mus musculus]] |
| + | [[Category: Finzel BC]] | ||
| + | [[Category: Liu LK]] | ||
Current revision
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
| |||||||||||
