5bto
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Scheffersomyces stipitis Rai1== | |
| - | + | <StructureSection load='5bto' size='340' side='right'caption='[[5bto]], [[Resolution|resolution]] 1.64Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5bto]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Scheffersomyces_stipitis_CBS_6054 Scheffersomyces stipitis CBS 6054]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BTO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.641Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bto OCA], [https://pdbe.org/5bto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bto RCSB], [https://www.ebi.ac.uk/pdbsum/5bto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bto ProSAT]</span></td></tr> |
| - | [[Category: Tong | + | </table> |
| - | [[Category: Wang | + | == Function == |
| + | [https://www.uniprot.org/uniprot/DXO_PICST DXO_PICST] Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA (By similarity). The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs (PubMed:26101253). Has decapping activity toward incomplete 5'-end m7G cap mRNAs such as unmethylated 5'-end-capped RNA (cap0), while it has no activity toward 2'-O-ribose methylated m7G cap (cap1) (By similarity).[UniProtKB:O13836][UniProtKB:O70348][UniProtKB:Q06349]<ref>PMID:26101253</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Scheffersomyces stipitis CBS 6054]] | ||
| + | [[Category: Tong L]] | ||
| + | [[Category: Wang VY]] | ||
Current revision
Crystal structure of Scheffersomyces stipitis Rai1
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