5bym
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA== | |
| - | + | <StructureSection load='5bym' size='340' side='right'caption='[[5bym]], [[Resolution|resolution]] 2.71Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5bym]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BYM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.708Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bym OCA], [https://pdbe.org/5bym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bym RCSB], [https://www.ebi.ac.uk/pdbsum/5bym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bym ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Hall | + | == Function == |
| + | [https://www.uniprot.org/uniprot/MPT5_YEAST MPT5_YEAST] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of HO by binding to the 3'-UTR of HO mRNA. Predominantly binds to mRNAs encoding chromatin modifiers and spindle pole body components. Recognizes and binds to 5'-TGTAA[CT]A[AT]TA-3' in the 3'-UTR of target mRNAs. Multicopy suppressor of POP2 mutation. Required for high temperature growth.<ref>PMID:11157761</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Hall TMT]] | ||
| + | [[Category: Qiu C]] | ||
Current revision
Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA
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