3cna

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[[Image:3cna.gif|left|200px]]
 
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{{Structure
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==STRUCTURE OF CONCANAVALIN A AT 2.4 ANGSTROMS RESOLUTION==
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|PDB= 3cna |SIZE=350|CAPTION= <scene name='initialview01'>3cna</scene>, resolution 2.4&Aring;
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<StructureSection load='3cna' size='340' side='right'caption='[[3cna]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
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<table><tr><td colspan='2'>[[3cna]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. The April 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Concanavalin A and Circular Permutation'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_4 10.2210/rcsb_pdb/mom_2010_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CNA FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cna OCA], [https://pdbe.org/3cna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cna RCSB], [https://www.ebi.ac.uk/pdbsum/3cna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cna ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CONA_CANEN CONA_CANEN] D-mannose specific lectin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/3cna_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cna ConSurf].
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<div style="clear:both"></div>
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'''STRUCTURE OF CONCANAVALIN A AT 2.4 ANGSTROMS RESOLUTION'''
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==See Also==
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*[[Concanavalin 3D structures|Concanavalin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3CNA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CNA OCA].
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==Reference==
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Structure of concanavalin A at 2.4-A resolution., Hardman KD, Ainsworth CF, Biochemistry. 1972 Dec 19;11(26):4910-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/4638345 4638345]
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[[Category: Canavalia ensiformis]]
[[Category: Canavalia ensiformis]]
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[[Category: Single protein]]
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[[Category: Concanavalin A and Circular Permutation]]
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[[Category: Ainsworth, C F.]]
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[[Category: Large Structures]]
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[[Category: Hardman, K D.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: CA]]
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[[Category: Ainsworth CF]]
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[[Category: MN]]
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[[Category: Hardman KD]]
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[[Category: lectin (agglutinin)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:04:08 2008''
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Current revision

STRUCTURE OF CONCANAVALIN A AT 2.4 ANGSTROMS RESOLUTION

PDB ID 3cna

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