4ymk

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==Crystal Structure of Stearoyl-Coenzyme A Desaturase 1==
==Crystal Structure of Stearoyl-Coenzyme A Desaturase 1==
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<StructureSection load='4ymk' size='340' side='right' caption='[[4ymk]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='4ymk' size='340' side='right'caption='[[4ymk]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ymk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YMK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ymk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YMK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPG:1-MONOOLEOYL-RAC-GLYCEROL'>MPG</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.605&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Stearoyl-CoA_9-desaturase Stearoyl-CoA 9-desaturase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.19.1 1.14.19.1] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPG:[(Z)-OCTADEC-9-ENYL]+(2R)-2,3-BIS(OXIDANYL)PROPANOATE'>MPG</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ymk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ymk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ymk RCSB], [http://www.ebi.ac.uk/pdbsum/4ymk PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ymk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ymk OCA], [https://pdbe.org/4ymk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ymk RCSB], [https://www.ebi.ac.uk/pdbsum/4ymk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ymk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACOD1_MOUSE ACOD1_MOUSE]] Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
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[https://www.uniprot.org/uniprot/ACOD1_MOUSE ACOD1_MOUSE] Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Stearoyl-CoA 9-desaturase]]
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[[Category: Large Structures]]
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[[Category: Bai, Y]]
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[[Category: Mus musculus]]
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[[Category: McCoy, J G]]
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[[Category: Bai Y]]
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[[Category: Rajashankar, K R]]
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[[Category: McCoy JG]]
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[[Category: Zhou, M]]
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[[Category: Rajashankar KR]]
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[[Category: Dimetal center]]
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[[Category: Zhou M]]

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Crystal Structure of Stearoyl-Coenzyme A Desaturase 1

PDB ID 4ymk

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