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4xfs

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==Structure of IL-18 SER Mutant I==
==Structure of IL-18 SER Mutant I==
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<StructureSection load='4xfs' size='340' side='right' caption='[[4xfs]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
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<StructureSection load='4xfs' size='340' side='right'caption='[[4xfs]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xfs]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XFS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xfs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XFS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xfs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xfs RCSB], [http://www.ebi.ac.uk/pdbsum/4xfs PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xfs OCA], [https://pdbe.org/4xfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xfs RCSB], [https://www.ebi.ac.uk/pdbsum/4xfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xfs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IL18_HUMAN IL18_HUMAN]] Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
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[https://www.uniprot.org/uniprot/IL18_HUMAN IL18_HUMAN] Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4xfs" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Interleukin 3D structures|Interleukin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Deng, J]]
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[[Category: Homo sapiens]]
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[[Category: Krumm, B E]]
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[[Category: Large Structures]]
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[[Category: Meng, X]]
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[[Category: Deng J]]
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[[Category: Xiang, Y]]
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[[Category: Krumm BE]]
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[[Category: Cytokine]]
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[[Category: Meng X]]
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[[Category: Il-18]]
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[[Category: Xiang Y]]
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[[Category: Immune defense]]
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[[Category: Interleukin-18]]
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[[Category: Surface entropy reduction]]
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Current revision

Structure of IL-18 SER Mutant I

PDB ID 4xfs

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