4o9i

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==Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding==
==Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding==
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<StructureSection load='4o9i' size='340' side='right' caption='[[4o9i]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='4o9i' size='340' side='right'caption='[[4o9i]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4o9i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O9I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4o9i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O9I FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o9i RCSB], [http://www.ebi.ac.uk/pdbsum/4o9i PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9i OCA], [https://pdbe.org/4o9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o9i RCSB], [https://www.ebi.ac.uk/pdbsum/4o9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o9i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN]] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>
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[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>
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==See Also==
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*[[Chromodomain-helicase-DNA-binding protein 3D structures|Chromodomain-helicase-DNA-binding protein 3D structures]]
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*[[Helicase 3D structures|Helicase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA helicase]]
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[[Category: Homo sapiens]]
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[[Category: Chruszcz, M]]
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[[Category: Large Structures]]
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[[Category: Khorasanizadeh, S]]
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[[Category: Chruszcz M]]
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[[Category: Minor, W]]
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[[Category: Khorasanizadeh S]]
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[[Category: Su, X]]
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[[Category: Minor W]]
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[[Category: Wiggs, K R]]
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[[Category: Su X]]
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[[Category: Chd4 double chromodomain]]
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[[Category: Wiggs KR]]
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[[Category: Hydrolase]]
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Current revision

Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding

PDB ID 4o9i

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