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4zol
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Tubulin-Stathmin-TTL-Tubulysin M Complex== | |
| + | <StructureSection load='4zol' size='340' side='right'caption='[[4zol]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4zol]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZOL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=55Q:(2R,4R)-4-{[(2-{(1R,3R)-1-(ACETYLOXY)-4-METHYL-3-[METHYL(N-{[(2S)-1-METHYLPIPERIDIN-2-YL]CARBONYL}-D-ISOLEUCYL)AMINO]PENTYL}-1,3-THIAZOL-4-YL)CARBONYL]AMINO}-2-METHYL-5-PHENYLPENTANOIC+ACID'>55Q</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zol OCA], [https://pdbe.org/4zol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zol RCSB], [https://www.ebi.ac.uk/pdbsum/4zol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zol ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
| - | + | ==See Also== | |
| - | + | *[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Wang | + | </StructureSection> |
| - | [[Category: Zhang | + | [[Category: Gallus gallus]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Sus scrofa]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Zhang R]] | ||
Current revision
Crystal Structure of Tubulin-Stathmin-TTL-Tubulysin M Complex
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