5cxy
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5cxy is ON HOLD Authors: Volkers, G., Strynadka, N.C.J. Description: Category: Unreleased Structures Category: Volkers, G [[Category: Stry...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a Glycosyltransferase in Complex with Inhibitor== | |
| + | <StructureSection load='5cxy' size='340' side='right'caption='[[5cxy]], [[Resolution|resolution]] 2.15Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5cxy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CXY FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=55T:5-O-[(R)-[(S)-[3-(ACETYLAMINO)PHENYL](PHOSPHONO)METHOXY](HYDROXY)PHOSPHORYL]CYTIDINE'>55T</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cxy OCA], [https://pdbe.org/5cxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cxy RCSB], [https://www.ebi.ac.uk/pdbsum/5cxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cxy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SIA8C_HUMAN SIA8C_HUMAN] May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.<ref>PMID:10766765</ref> <ref>PMID:9826427</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Sialyltransferase 3D structures|Sialyltransferase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Strynadka NCJ]] | ||
| + | [[Category: Volkers G]] | ||
Current revision
Structure of a Glycosyltransferase in Complex with Inhibitor
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