4oki

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==X-ray structure of the nucleotide-binding subdomain of the enoylreductase domain of PpsC from Mycobacterium tuberculosis==
==X-ray structure of the nucleotide-binding subdomain of the enoylreductase domain of PpsC from Mycobacterium tuberculosis==
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<StructureSection load='4oki' size='340' side='right' caption='[[4oki]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='4oki' size='340' side='right'caption='[[4oki]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4oki]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OKI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4oki]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OKI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_I Beta-ketoacyl-[acyl-carrier-protein] synthase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.41 2.3.1.41] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oki OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oki RCSB], [http://www.ebi.ac.uk/pdbsum/4oki PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oki OCA], [https://pdbe.org/4oki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oki RCSB], [https://www.ebi.ac.uk/pdbsum/4oki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oki ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PPSC_MYCTU PPSC_MYCTU]] Involved in the elongation of either C22-24 fatty acids by the addition of malonyl-CoA and methylmalonyl-CoA extender units to yield phthiocerol derivatives.
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[https://www.uniprot.org/uniprot/PPSC_MYCTU PPSC_MYCTU] Involved in the elongation of either C22-24 fatty acids by the addition of malonyl-CoA and methylmalonyl-CoA extender units to yield phthiocerol derivatives.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Faille, A]]
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[[Category: Large Structures]]
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[[Category: Mourey, L]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Pedelacq, J D]]
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[[Category: Faille A]]
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[[Category: Enoylreductase]]
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[[Category: Mourey L]]
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[[Category: Transferase]]
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[[Category: Pedelacq JD]]

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X-ray structure of the nucleotide-binding subdomain of the enoylreductase domain of PpsC from Mycobacterium tuberculosis

PDB ID 4oki

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