3jav

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'''Unreleased structure'''
 
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The entry 3jav is ON HOLD until Paper Publication
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==Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM==
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<SX load='3jav' size='340' side='right' viewer='molstar' caption='[[3jav]], [[Resolution|resolution]] 4.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3jav]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JAV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jav OCA], [https://pdbe.org/3jav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jav RCSB], [https://www.ebi.ac.uk/pdbsum/3jav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jav ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ITPR1_RAT ITPR1_RAT] Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
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Authors: Fan, G., Baker, M.L., Wang, Z., Baker, M.R., Sinyagovskiy, P.A., Chiu, W., Ludtke, S.J., Serysheva, I.I.
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==See Also==
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*[[Inositol 1%2C4%2C5-Trisphosphate Receptor|Inositol 1%2C4%2C5-Trisphosphate Receptor]]
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Description: Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM
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__TOC__
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[[Category: Unreleased Structures]]
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</SX>
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[[Category: Baker, M.R]]
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[[Category: Large Structures]]
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[[Category: Baker, M.L]]
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[[Category: Rattus norvegicus]]
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[[Category: Fan, G]]
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[[Category: Baker ML]]
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[[Category: Sinyagovskiy, P.A]]
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[[Category: Baker MR]]
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[[Category: Chiu, W]]
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[[Category: Chiu W]]
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[[Category: Serysheva, I.I]]
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[[Category: Fan G]]
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[[Category: Ludtke, S.J]]
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[[Category: Ludtke SJ]]
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[[Category: Wang, Z]]
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[[Category: Serysheva II]]
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[[Category: Sinyagovskiy PA]]
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[[Category: Wang Z]]

Current revision

Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM

3jav, resolution 4.70Å

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