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1a9c

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[[Image:1a9c.gif|left|200px]]
 
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{{Structure
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==GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP==
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|PDB= 1a9c |SIZE=350|CAPTION= <scene name='initialview01'>1a9c</scene>, resolution 2.9&Aring;
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<StructureSection load='1a9c' size='340' side='right'caption='[[1a9c]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=GTP:GUANOSINE-5&#39;-TRIPHOSPHATE'>GTP</scene>
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<table><tr><td colspan='2'>[[1a9c]] is a 15 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A9C FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a9c OCA], [https://pdbe.org/1a9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a9c RCSB], [https://www.ebi.ac.uk/pdbsum/1a9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a9c ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GCH1_ECOLI GCH1_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a9/1a9c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a9c ConSurf].
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<div style="clear:both"></div>
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'''GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP'''
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==See Also==
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*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1A9C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9C OCA].
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: GTP cyclohydrolase I]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Auerbach G]]
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[[Category: Auerbach, G.]]
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[[Category: Bacher A]]
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[[Category: Bacher, A.]]
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[[Category: Bracher A]]
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[[Category: Bracher, A.]]
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[[Category: Huber R]]
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[[Category: Huber, R.]]
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[[Category: Nar H]]
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[[Category: Nar, H.]]
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[[Category: GTP]]
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[[Category: gtp]]
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[[Category: hydrolase]]
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[[Category: pterine synthesis]]
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[[Category: purine hydrolysis]]
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[[Category: tetrahydrobiopterin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 23 11:05:26 2008''
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Current revision

GTP CYCLOHYDROLASE I (C110S MUTANT) IN COMPLEX WITH GTP

PDB ID 1a9c

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