5d0u
From Proteopedia
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(New page: '''Unreleased structure''' The entry 5d0u is ON HOLD until Paper Publication Authors: Tauchert, M.J., Ficner, R. Description: Category: Unreleased Structures [[Category: Tauchert,...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP== | |
| + | <StructureSection load='5d0u' size='340' side='right'caption='[[5d0u]], [[Resolution|resolution]] 2.92Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5d0u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum_var._thermophilum_DSM_1495 Chaetomium thermophilum var. thermophilum DSM 1495]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D0U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.919Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d0u OCA], [https://pdbe.org/5d0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d0u RCSB], [https://www.ebi.ac.uk/pdbsum/5d0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d0u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/G0RY84_CHATD G0RY84_CHATD] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | RNA helicases are indispensable for all organisms in each domain of life and have implications in numerous cellular processes. The DEAH-box RNA helicase Prp43 is involved in pre-mRNA splicing as well as rRNA maturation. Here, the crystal structure of Chaetomium thermophilum Prp43 at 2.9 A resolution is revealed. Furthermore, it is demonstrated that Prp43 from C. thermophilum is capable of functionally replacing its orthologue from Saccharomyces cerevisiae in spliceosomal disassembly assays. | ||
| - | + | Structural and functional analysis of the RNA helicase Prp43 from the thermophilic eukaryote Chaetomium thermophilum.,Tauchert MJ, Fourmann JB, Christian H, Luhrmann R, Ficner R Acta Crystallogr F Struct Biol Commun. 2016 Feb;72(Pt 2):112-20. doi:, 10.1107/S2053230X15024498. Epub 2016 Jan 22. PMID:26841761<ref>PMID:26841761</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: | + | <div class="pdbe-citations 5d0u" style="background-color:#fffaf0;"></div> |
| - | [[Category: Ficner | + | |
| + | ==See Also== | ||
| + | *[[Helicase 3D structures|Helicase 3D structures]] | ||
| + | *[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chaetomium thermophilum var. thermophilum DSM 1495]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ficner R]] | ||
| + | [[Category: Tauchert MJ]] | ||
Current revision
Crystal structure of the RNA-helicase Prp43 from Chaetomium thermophilum bound to ADP
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