This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4r5r
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of Rhodostomin KKKRT mutant== | ==Crystal structure of Rhodostomin KKKRT mutant== | ||
| - | <StructureSection load='4r5r' size='340' side='right' caption='[[4r5r]], [[Resolution|resolution]] 0.96Å' scene=''> | + | <StructureSection load='4r5r' size='340' side='right'caption='[[4r5r]], [[Resolution|resolution]] 0.96Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4r5r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5R OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4r5r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R5R FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5r OCA], [https://pdbe.org/4r5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r5r RCSB], [https://www.ebi.ac.uk/pdbsum/4r5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r5r ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). |
| + | |||
| + | ==See Also== | ||
| + | *[[Disintegrin|Disintegrin]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Calloselasma rhodostoma]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Chang YT]] |
| - | [[Category: | + | [[Category: Chuang WJ]] |
| - | [[Category: | + | [[Category: Huang CH]] |
| - | [[Category: | + | [[Category: Jeng WY]] |
| - | [[Category: | + | [[Category: Shiu JH]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of Rhodostomin KKKRT mutant
| |||||||||||
