4v60
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==The structure of rat liver vault at 3.5 angstrom resolution== | ==The structure of rat liver vault at 3.5 angstrom resolution== | ||
| - | <StructureSection load='4v60' size='340' side='right' caption='[[4v60]], [[Resolution|resolution]] 3.50Å' scene=''> | + | <StructureSection load='4v60' size='340' side='right'caption='[[4v60]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4v60]] is a 39 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4v60]] is a 39 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zuo 2zuo], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv4 2zv4] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zv5 2zv5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V60 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v60 OCA], [https://pdbe.org/4v60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v60 RCSB], [https://www.ebi.ac.uk/pdbsum/4v60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v60 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | {{Large structure}} | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MVP_RAT MVP_RAT] Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases (By similarity). |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Kato | + | [[Category: Kato K]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka H]] |
| - | [[Category: Tsukihara | + | [[Category: Tsukihara T]] |
| - | [[Category: Yamashita | + | [[Category: Yamashita E]] |
| - | [[Category: Yao | + | [[Category: Yao M]] |
| - | [[Category: Yoshimura | + | [[Category: Yoshimura M]] |
| - | [[Category: Zhou | + | [[Category: Zhou Y]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
The structure of rat liver vault at 3.5 angstrom resolution
| |||||||||||
Categories: Large Structures | Rattus norvegicus | Kato K | Tanaka H | Tsukihara T | Yamashita E | Yao M | Yoshimura M | Zhou Y
