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NADP-dependent malic enzyme
From Proteopedia
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| - | + | <StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''> | |
| - | <StructureSection load=' | + | Best example is PDB entry [[3wja]] and is shown in the viewer.<br> |
| - | + | ==Catalytic Activity == | |
| - | + | Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br> | |
| + | Or the decarboxylation of malate to pyruvate<ref>PMID:8187880</ref>. | ||
| - | == | + | == Biological process == |
| + | Is involved in the following biological processes:<br> | ||
| + | malate metabolic process<br> | ||
| + | oxidation-reduction process<br> | ||
| + | response to carbohydrate<br> | ||
| + | response to hormone<br> | ||
| + | carbohydrate metabolic process<br> | ||
| + | protein tetramerization<br> | ||
| + | regulation of NADP metabolic process<br> | ||
| + | NADP biosynthetic process<br> | ||
| + | small molecule metabolic process<br> | ||
| + | cellular lipid metabolic process<br> | ||
| + | == In structures == | ||
| + | NADP-dependent malic enzyme is found in 3 PDB entries<br> | ||
| + | *<b>Eukaryota</b> (3 PDB entries): <br> | ||
| + | **<b>Homo sapiens</b> (2 PDB entries): <br> | ||
| + | ***[[3wja]] <div class="pdb-prints 3wja"></div> | ||
| + | ***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form | ||
| + | ***2.548 A resolution | ||
| + | ***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search the PDB for NADP-dependent malic enzyme from Homo sapiens] | ||
| + | **<b>Columba livia</b> (1 PDB entries): <br> | ||
| + | ***[[1gq2]] <div class="pdb-prints 1gq2"></div> | ||
| + | ***Title: MALIC ENZYME FROM PIGEON LIVER | ||
| + | ***2.5 A resolution | ||
| + | == Alternative names for NADP-dependent malic enzyme == | ||
| + | Molecule '''NADP-dependent malic enzyme''', also known as '''NADP-ME''', '''NADP-dependent malic enzyme''' and '''Malic enzyme 1'''. | ||
| - | == | + | == 3D Structures of NADP-dependent malic enzyme == |
| - | + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | |
| + | |||
| - | + | [[3wja]], [[2aw5]] – hME - human<br /> | |
| + | [[7x11]], [[7x12]] – hME1 + NADP<br /> | ||
| + | [[8e76]], [[8eyn]] – hME3<br /> | ||
| + | [[8e78]], [[8e8o]], [[8eyo]] – hME3 + NADP<br /> | ||
| + | [[1gq2]] – ME + NADP - pigeon<br /> | ||
| + | [[5ou5]] – ME - maize<br /> | ||
| - | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
| - | |||
| - | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
| + | [[Category:Topic Page]][[Category:PDBe]] | ||
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