NADP-dependent malic enzyme

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==Your Heading Here (maybe something like 'Structure')==
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<StructureSection load='3wja' size='340' side='right' caption='The best structure for NADP-dependent malic enzyme shown: [[3wja]]' scene=''>
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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
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Best example is PDB entry [[3wja]] and is shown in the viewer.<br>
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This is a default text for your page '''NADP-dependent malic enzyme'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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==Catalytic Activity ==
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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Oxaloacetate = pyruvate + CO(2).Data source: Uniprot [http://www.uniprot.org/uniprot/P48163 P48163]<br>
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Or the decarboxylation of malate to pyruvate<ref>PMID:8187880</ref>.
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== Function ==
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== Biological process ==
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Is involved in the following biological processes:<br>
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malate metabolic process<br>
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oxidation-reduction process<br>
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response to carbohydrate<br>
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response to hormone<br>
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carbohydrate metabolic process<br>
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protein tetramerization<br>
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regulation of NADP metabolic process<br>
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NADP biosynthetic process<br>
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small molecule metabolic process<br>
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cellular lipid metabolic process<br>
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== In structures ==
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NADP-dependent malic enzyme is found in 3 PDB entries<br>
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*<b>Eukaryota</b> (3 PDB entries): <br>
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**<b>Homo sapiens</b> (2 PDB entries): <br>
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***[[3wja]] <div class="pdb-prints 3wja"></div>
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***Title: The crystal structure of human cytosolic NADP(+)-dependent malic enzyme in apo form
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***2.548 A resolution
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***[http://www.ebi.ac.uk/pdbe/entry/search/index?organism_scientific_name:%22Homo%20sapiens%22&all_molecule_names:%22NADP-dependent%20malic%20enzyme%22&!chimera:y Search the PDB for NADP-dependent malic enzyme from Homo sapiens]
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**<b>Columba livia</b> (1 PDB entries): <br>
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***[[1gq2]] <div class="pdb-prints 1gq2"></div>
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***Title: MALIC ENZYME FROM PIGEON LIVER
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***2.5 A resolution
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== Alternative names for NADP-dependent malic enzyme ==
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Molecule '''NADP-dependent malic enzyme''', also known as '''NADP-ME''', '''NADP-dependent malic enzyme''' and '''Malic enzyme 1'''.
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== Disease ==
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== 3D Structures of NADP-dependent malic enzyme ==
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== Relevance ==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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== Structural highlights ==
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[[3wja]], [[2aw5]] – hME - human<br />
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[[7x11]], [[7x12]] – hME1 + NADP<br />
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[[8e76]], [[8eyn]] – hME3<br />
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[[8e78]], [[8e8o]], [[8eyo]] – hME3 + NADP<br />
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[[1gq2]] – ME + NADP - pigeon<br />
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[[5ou5]] – ME - maize<br />
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This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
 
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</StructureSection>
 
== References ==
== References ==
<references/>
<references/>
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[[Category:Topic Page]][[Category:PDBe]]

Current revision

The best structure for NADP-dependent malic enzyme shown: 3wja

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

PDBe, Jaime Prilusky, Michal Harel

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