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4rci

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==Crystal structure of YTHDF1 YTH domain==
==Crystal structure of YTHDF1 YTH domain==
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<StructureSection load='4rci' size='340' side='right' caption='[[4rci]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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<StructureSection load='4rci' size='340' side='right'caption='[[4rci]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rci]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RCI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rci]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RCI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RCI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rcj|4rcj]], [[4rcm|4rcm]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rci OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rci RCSB], [http://www.ebi.ac.uk/pdbsum/4rci PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rci OCA], [https://pdbe.org/4rci PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rci RCSB], [https://www.ebi.ac.uk/pdbsum/4rci PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rci ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/YTHD1_HUMAN YTHD1_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.<ref>PMID:24284625</ref>
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[https://www.uniprot.org/uniprot/YTHD1_HUMAN YTHD1_HUMAN] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability.<ref>PMID:24284625</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4rci" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arrowsmith, C H]]
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[[Category: Homo sapiens]]
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[[Category: Bountra, C]]
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[[Category: Large Structures]]
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[[Category: Edwards, A M]]
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[[Category: Arrowsmith CH]]
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[[Category: Liu, K]]
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[[Category: Bountra C]]
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[[Category: Min, J]]
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[[Category: Edwards AM]]
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[[Category: Structural genomic]]
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[[Category: Liu K]]
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[[Category: Tempel, W]]
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[[Category: Min J]]
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[[Category: Walker, J R]]
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[[Category: Tempel W]]
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[[Category: Xu, C]]
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[[Category: Walker JR]]
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[[Category: Rna binding protein]]
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[[Category: Xu C]]
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[[Category: Sgc]]
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Current revision

Crystal structure of YTHDF1 YTH domain

PDB ID 4rci

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