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1obb
From Proteopedia
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==alpha-glucosidase A, AglA, from Thermotoga maritima in complex with maltose and NAD+== | ==alpha-glucosidase A, AglA, from Thermotoga maritima in complex with maltose and NAD+== | ||
| - | <StructureSection load='1obb' size='340' side='right' caption='[[1obb]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='1obb' size='340' side='right'caption='[[1obb]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1obb]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1obb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OBB FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PRD_900001:alpha-maltose'>PRD_900001</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1obb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1obb OCA], [https://pdbe.org/1obb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1obb RCSB], [https://www.ebi.ac.uk/pdbsum/1obb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1obb ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/AGLA_THEMA AGLA_THEMA] alpha-glycosidase with a very broad specificity hydrolyzes maltose and other small maltooligosaccharides but is inactive against the polymeric substrate starch agla is not specific with respect to the configuration at the c-4 position of its substrates because glycosidic derivatives of d-galactose are also hydrolyzed does not cleave beta-glycosidic bonds |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1obb_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ob/1obb_consurf.spt"</scriptWhenChecked> |
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1obb ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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==See Also== | ==See Also== | ||
| - | *[[Alpha-glucosidase|Alpha-glucosidase]] | + | *[[Alpha-glucosidase 3D structures|Alpha-glucosidase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Thermotoga maritima MSB8]] |
| - | [[Category: Hoffmann | + | [[Category: Hoffmann V]] |
| - | [[Category: Liebl | + | [[Category: Liebl W]] |
| - | [[Category: Lodge | + | [[Category: Lodge JA]] |
| - | [[Category: Maier | + | [[Category: Maier T]] |
| - | [[Category: Strater | + | [[Category: Strater N]] |
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Current revision
alpha-glucosidase A, AglA, from Thermotoga maritima in complex with maltose and NAD+
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