1iqp

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==Crystal Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus==
==Crystal Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus==
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<StructureSection load='1iqp' size='340' side='right' caption='[[1iqp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='1iqp' size='340' side='right'caption='[[1iqp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1iqp]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IQP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IQP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1iqp]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IQP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rfcs ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iqp OCA], [http://pdbe.org/1iqp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iqp RCSB], [http://www.ebi.ac.uk/pdbsum/1iqp PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iqp OCA], [https://pdbe.org/1iqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iqp RCSB], [https://www.ebi.ac.uk/pdbsum/1iqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iqp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RFCS_PYRFU RFCS_PYRFU]] Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA.<ref>PMID:11274122</ref> <ref>PMID:12296822</ref>
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[https://www.uniprot.org/uniprot/RFCS_PYRFU RFCS_PYRFU] Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA.<ref>PMID:11274122</ref> <ref>PMID:12296822</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/1iqp_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/1iqp_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iqp ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 43587]]
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[[Category: Large Structures]]
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[[Category: Cann, I K.O]]
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[[Category: Pyrococcus furiosus]]
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[[Category: Ishino, S]]
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[[Category: Cann IKO]]
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[[Category: Ishino, Y]]
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[[Category: Ishino S]]
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[[Category: Morikawa, K]]
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[[Category: Ishino Y]]
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[[Category: Oyama, T]]
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[[Category: Morikawa K]]
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[[Category: Clamp loader]]
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[[Category: Oyama T]]
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[[Category: Complex with adp]]
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[[Category: Extended aaa-atpase domain]]
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[[Category: Replication]]
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Current revision

Crystal Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus

PDB ID 1iqp

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