1w5s

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==STRUCTURE OF THE AEROPYRUM PERNIX ORC2 PROTEIN (ADP FORM)==
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<StructureSection load='1w5s' size='340' side='right' caption='[[1w5s]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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==Structure of the Aeropyrum Pernix ORC2 protein (ADP form)==
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<StructureSection load='1w5s' size='340' side='right'caption='[[1w5s]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1w5s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aerpx Aerpx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W5S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1w5s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W5S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w5t|1w5t]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5s OCA], [http://pdbe.org/1w5s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w5s RCSB], [http://www.ebi.ac.uk/pdbsum/1w5s PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w5s OCA], [https://pdbe.org/1w5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w5s RCSB], [https://www.ebi.ac.uk/pdbsum/1w5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w5s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CDC62_AERPE CDC62_AERPE]] Involved in regulation of DNA replication (By similarity). Binds DNA.[HAMAP-Rule:MF_01407]<ref>PMID:15465044</ref>
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[https://www.uniprot.org/uniprot/CDC62_AERPE CDC62_AERPE] Involved in regulation of DNA replication (By similarity). Binds DNA.[HAMAP-Rule:MF_01407]<ref>PMID:15465044</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/1w5s_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w5/1w5s_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w5s ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aerpx]]
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[[Category: Aeropyrum pernix]]
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[[Category: Cook, N]]
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[[Category: Large Structures]]
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[[Category: Grainge, I]]
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[[Category: Cook N]]
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[[Category: Isupov, M N]]
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[[Category: Grainge I]]
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[[Category: Morales, R]]
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[[Category: Isupov MN]]
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[[Category: Singleton, M R]]
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[[Category: Morales R]]
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[[Category: Wigley, D B]]
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[[Category: Singleton MR]]
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[[Category: Aaa+ atpase]]
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[[Category: Wigley DB]]
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[[Category: Cdc6]]
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[[Category: Dna binding protein]]
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[[Category: Dna replication initiation]]
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[[Category: Orc]]
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[[Category: Replication]]
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Current revision

Structure of the Aeropyrum Pernix ORC2 protein (ADP form)

PDB ID 1w5s

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OCA

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