1sn5

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==Crystal Structure of Sea Bream Transthyretin in complex with Triiodothyronine at 1.90A Resolution==
==Crystal Structure of Sea Bream Transthyretin in complex with Triiodothyronine at 1.90A Resolution==
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<StructureSection load='1sn5' size='340' side='right' caption='[[1sn5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='1sn5' size='340' side='right'caption='[[1sn5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1sn5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aurata_aurata Aurata aurata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SN5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SN5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1sn5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sparus_aurata Sparus aurata]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SN5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SN5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T3:3,5,3TRIIODOTHYRONINE'>T3</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1sn0|1sn0]], [[1sn2|1sn2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=T3:3,5,3TRIIODOTHYRONINE'>T3</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sn5 OCA], [http://pdbe.org/1sn5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1sn5 RCSB], [http://www.ebi.ac.uk/pdbsum/1sn5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sn5 OCA], [https://pdbe.org/1sn5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sn5 RCSB], [https://www.ebi.ac.uk/pdbsum/1sn5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sn5 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9PTT3_SPAAU Q9PTT3_SPAAU]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sn/1sn5_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sn/1sn5_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sn5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Transthyretin|Transthyretin]]
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*[[Transthyretin 3D structures|Transthyretin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aurata aurata]]
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[[Category: Large Structures]]
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[[Category: Cantos, C R]]
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[[Category: Sparus aurata]]
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[[Category: Eneqvist, T]]
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[[Category: Cantos CR]]
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[[Category: Huang, S]]
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[[Category: Eneqvist T]]
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[[Category: Karlsson, A]]
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[[Category: Huang S]]
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[[Category: Lundberg, E]]
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[[Category: Karlsson A]]
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[[Category: Power, D M]]
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[[Category: Lundberg E]]
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[[Category: Sauer-Eriksson, A E]]
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[[Category: Power DM]]
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[[Category: Transport protein]]
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[[Category: Sauer-Eriksson AE]]

Current revision

Crystal Structure of Sea Bream Transthyretin in complex with Triiodothyronine at 1.90A Resolution

PDB ID 1sn5

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