1gxw

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==the 2.2 A resolution structure of thermolysin crystallized in presence of potassium thiocyanate==
==the 2.2 A resolution structure of thermolysin crystallized in presence of potassium thiocyanate==
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<StructureSection load='1gxw' size='340' side='right' caption='[[1gxw]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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<StructureSection load='1gxw' size='340' side='right'caption='[[1gxw]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1gxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GXW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1gxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GXW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fj3|1fj3]], [[1fjo|1fjo]], [[1fjq|1fjq]], [[1fjt|1fjt]], [[1fju|1fju]], [[1fjv|1fjv]], [[1fjw|1fjw]], [[1hyt|1hyt]], [[1lna|1lna]], [[1lnb|1lnb]], [[1lnc|1lnc]], [[1lnd|1lnd]], [[1lne|1lne]], [[1lnf|1lnf]], [[1qf0|1qf0]], [[1qf1|1qf1]], [[1qf2|1qf2]], [[1thl|1thl]], [[1tli|1tli]], [[1tlp|1tlp]], [[1tlx|1tlx]], [[1tmn|1tmn]], [[1trl|1trl]], [[2tli|2tli]], [[2tlx|2tlx]], [[2tmn|2tmn]], [[3tli|3tli]], [[3tmn|3tmn]], [[4tli|4tli]], [[4tln|4tln]], [[4tmn|4tmn]], [[5tli|5tli]], [[5tln|5tln]], [[5tmn|5tmn]], [[6tli|6tli]], [[6tmn|6tmn]], [[7tli|7tli]], [[7tln|7tln]], [[8tli|8tli]], [[8tln|8tln]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxw OCA], [https://pdbe.org/1gxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gxw RCSB], [https://www.ebi.ac.uk/pdbsum/1gxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gxw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gxw OCA], [http://pdbe.org/1gxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gxw RCSB], [http://www.ebi.ac.uk/pdbsum/1gxw PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
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[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxw_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gx/1gxw_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gxw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
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*[[Thermolysin|Thermolysin]]
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*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
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[[Category: Thermolysin]]
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[[Category: Large Structures]]
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[[Category: Gaucher, J F]]
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[[Category: Gaucher JF]]
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[[Category: Prange, T]]
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[[Category: Prange T]]
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[[Category: Selkti, M]]
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[[Category: Selkti M]]
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[[Category: Tomas, A]]
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[[Category: Tomas A]]
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[[Category: Hydrolase]]
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[[Category: Metalloendopeptidase]]
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[[Category: Metalloprotease]]
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[[Category: Salting-in]]
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[[Category: Thiocyanate]]
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Current revision

the 2.2 A resolution structure of thermolysin crystallized in presence of potassium thiocyanate

PDB ID 1gxw

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