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2poe
From Proteopedia
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==Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660== | ==Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660== | ||
| - | <StructureSection load='2poe' size='340' side='right' caption='[[2poe]], [[Resolution|resolution]] 2.01Å' scene=''> | + | <StructureSection load='2poe' size='340' side='right'caption='[[2poe]], [[Resolution|resolution]] 2.01Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2poe]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2poe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2POE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2POE FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2poe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2poe OCA], [https://pdbe.org/2poe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2poe RCSB], [https://www.ebi.ac.uk/pdbsum/2poe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2poe ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/A3FQ68_CRYPI A3FQ68_CRYPI] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.[RuleBase:RU004223] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poe_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/po/2poe_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2poe ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Cryptosporidium parvum Iowa II]] |
| - | [[Category: Amani | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Amani M]] |
| - | [[Category: Artz | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bochkarev | + | [[Category: Artz JD]] |
| - | [[Category: Edwards | + | [[Category: Bochkarev A]] |
| - | [[Category: Hassanali | + | [[Category: Edwards AM]] |
| - | [[Category: Hills | + | [[Category: Hassanali A]] |
| - | [[Category: Hui | + | [[Category: Hills T]] |
| - | [[Category: Kozieradzki | + | [[Category: Hui R]] |
| - | [[Category: Lew | + | [[Category: Kozieradzki I]] |
| - | [[Category: Lin | + | [[Category: Lew J]] |
| - | + | [[Category: Lin L]] | |
| - | [[Category: Schapira | + | [[Category: Schapira M]] |
| - | [[Category: Sundstrom | + | [[Category: Sundstrom M]] |
| - | [[Category: Vedadi | + | [[Category: Vedadi M]] |
| - | [[Category: Wasney | + | [[Category: Wasney G]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Wernimont | + | [[Category: Wernimont AK]] |
| - | [[Category: Zhao | + | [[Category: Zhao Y]] |
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Current revision
Crystal structure of Cryptosporidium parvum cyclophilin type peptidyl-prolyl cis-trans isomerase cgd2_1660
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Categories: Cryptosporidium parvum Iowa II | Large Structures | Amani M | Arrowsmith CH | Artz JD | Bochkarev A | Edwards AM | Hassanali A | Hills T | Hui R | Kozieradzki I | Lew J | Lin L | Schapira M | Sundstrom M | Vedadi M | Wasney G | Weigelt J | Wernimont AK | Zhao Y
